I have played with CCLeaner before but never ran the cleaner. After I analyze a lot of files will show up and I think to myself, "is it worth crashing the computer if the wrong thing is erased?"
As an example: under Hotfix uninstallers I'll see C:\WINDOWS\$NtUninstallKB873339$\eula.txt 4.00KB. Ok it is a text file and I would not see why it couldn't be removed.
Then there is this: C:\WINDOWS\$NtUninstallKB873339$\update.exe 0.62MB. Now an executible file, hm? That could be present a problem.
I just don't know what the best protocol is for using a cleaner. Years ago I used one on a desktop and it created a lot of problems.