I have been using CCleaner for MANY years now and have always been very happy with it. It is only recently that I went Pro though - with version 5.22, which immediately upgraded to 5.23. I never had any issues until then... I have never got a Windows 10 Message stating it is removing my copy of CCleaner, even when I upgraded to the Windows Anniversary Edition!
I'm running Windows 10 Home Version 1607, Build 14931.1000 - the latest in the Slow Insider Ring, on a Samsung Laptop with an i5 Processor, 8 GB RAM, 1 TB HDD, 14" Touch Screen, Built-in Graphics. It is after upgrading to CCleaner 5.23, that I observed that whenever CCleaner did an auto clean, my Desktop Icons get all messed up! Nothing is missing, just that they are not where they used to be!! This is rather irky, since I prefer to know exactly where my icons are, like most users!! When this happens, CCleaner finds over 750 MB to clean each time too, which it does faithfully!
It may be a quirk of Windows 10, but I sure hope Piriform can do something to solve it in the next update! If you want any more details about my Software/ Hardware, I'll gladly supply the same! There is nothing but my Desktop - before and after it happens - that I can attach as screenshots, so if that will help, I can attach them too...
Meanwhile, Three Cheers for a GREAT Product!!!