Hello again K,
Just to let you know I seemed to have fixed the problem but exactly how I did it I'm not sure ! This afternoon, just out of curiosity, I loaded a piece of freebie software called 'PC Booster' (bluesquad.co.uk) which came on a cover disk with a recently purchased magazine, Computer Shopper(I'm in the UK, I don't know if you have it over there??). Anyway, after running the software and rebooting I tried out some of my programs just to see if it had made any difference to performance (which it had!). I also tried CCleaner and lo and behold it was working as per normal again !
Although I'm not sure exactly what cured the problem it hasn't been a wasted exercise. As the saying goes, "Never a day is wasted when you've learnt something new" and I've learnt one or two new things along the way. Many thanks once again for your efforts, K. and also Andavari and Glenn.
Cheers,
Allan