Actually this is a problem with ZoneAlarm (also present in a number of other applications, such as Adobe's Reader 8.0), where the application changes its icon pointer to an icon that isn't embedded within the application each time you run the application.
ZoneAlarm embeds its MailSafe into many email applications (such as Outlook Express) and each time you run your email application the icon pointer is changed resulting in a brand new problem for CCleaner to fix.
Jef