Going to check around a bit. More interested in what it conflicts with than anything else.
edit. after a quick look:
Reviewers seem to like but are being cautious.
just installed it ran a quick scan, 9 minutes, and a selective scan.
Looks pretty good, configurable, offers options to remove, quarantine, or restore for found threats.
No reboot required, so can be tested under returnil or powershadow. edit: well, reboot required to upgrade.
No conflicts with preinstalled avast, spywareguard, spywareblaster, or spybot.
But I wouldn't run it concurrent with avast unless one of the spyware moderators on here said that is OK.
realtime protection found a double zipped eicar test file and a zipped rootkit when I tried to copy them.
Selective scan found both, also.
Looks pretty good here, so far.
Going to run a full scan now, then reboot out of powershadow.
If I don't come back, send a big dog with a flask.

Edit #2: didn't run the full scan, had to quit, so don't know how long. For me the best news is that it will install, run, scan, and find under Returnil or PS.