I'm using Defraggler v1.13.155 and I'm having trouble defragmenting Kaspersky Internet Security files on WinXP. I've included a screenshot of Defraggler after it finished defragmenting my drive. Thanks for the help.

There should be a "Disable self-protection" option in KIS's settings :-)

Is that the only way? Won't that be bad if KIS get's attacked?

It won't. Defraggler is using the Windows API to move files.

Don't forget to enable the self-protection again after you defrag :-)

I'm more concerned about KIS being attack from the net while I'm connected. But I guess there's no avoiding it right now. I'll just have to disconnect my Ethernet while Defraggler is running, just in case.