Probably not because it would have to search the whole system partition, and having it do such has been discussed recently with people wanting to remove things like thumbs.db.
If you get those pesky files from downloading allot of free icons you can use something like this on your download folder to remove them all. The example below uses C:\Downloads however you can change the path. Just save as a batch file like "Remove DS_Store.bat":
attrib /s -r -h -s "C:\Downloads\*.DS_Store"
del /q /s "C:\Downloads\*.DS_Store"